The Interdisciplinary Center for Scientific Computing (IWR) and its affiliated institutions organize a large number of workshops, conferences and other events for discussing latest scientific results as well as identifing upcoming challenges in the field of Scientific Computing. In addition the IWR regularly hosts events which emphasis on broadening and improving the interdisciplinary dialogue.
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January 20, 2021 • 16:30 • Virtual Talks
"Linking neural circuits to behavior: the need of quantitative approaches to assess naturalistic behaviors"
Dr. Claudio Acuna • Laboratory of Neural Circuits and Behavior, Institute of Anatomy and Cell Biology, Heidelberg University
Our lab is interested in understanding the molecular, synaptic and circuit basis of innate social behaviors and its dysregulation in devastating neuropsychiatric diseases such as autism and schizophrenia. In this talk, I will discuss our recent progress in understanding how long-range cerebellar outputs promote and regulate social interactions, and how dysfunction of these circuits might contribute to autism pathogenesis. I will also discuss the value of using quantitative approaches to study naturalistic social interactions, our current attempts to implement these approaches in the lab, and the need of establishing multidisciplinary teams to tackle these challenging questions.
Dr. Anthony Hill • Neuronal Signaling and Morphogeneis Laboratory, German Cancer Research Center (DKFZ)
Our goal is to understand the molecular and cellular mechanisms regulating choroid plexus tumor (CPT) progression. We are using single cell RNAseq and ATACseq of normal and tumorous human choroid plexus to analyze the genetic and epigenetic events leading to CPT initiation, growth and survival. From these raw data we can quantitate tumor associated changes in immune cell invasion and activation, cellular signaling and transcriptional regulation and trace the lineage of choroid plexus tumor cells. This work will involve computationally integrating multiple analyses to create a holistic view of choroid plexus tumor progression.
The virtual talks will be held via ZOOM. For more information please visit the webpage of the IWR Colloquium.
Last Update: 11.01.2021 - 16:46